TY - CHAP M1 - Book, Section TI - Miscellaneous Bacterial Infections with Cutaneous Manifestations A1 - Norton, Scott A. A1 - Cardis, Michael A. A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEA large Gram-positive rod, Bacillus anthracis, changes into dormant spores under environmentally harsh conditions. Spores are infectious particles that revert to active bacillary form in host tissues.Natural pathogen of livestock, especially sheep, goats, and cattle. Most human diseases are occupationally related to exposure to live animals or animal products.Cutaneous anthrax is the most common form and is associated with the lowest morbidity. Inhalational and GI anthrax are more virulent and frequently lethal.Cutaneous lesions arise from percutaneous spore inoculation, usually unnoticed. They present as painless edematous papules or plaques that develop jet-black central eschars.The organism is a Centers for Disease Control and Prevention Category A bioweapon in aerosolizable micropowder form. There is no potential for human-to-human transmission of inhalational anthrax. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161352508 ER -