TY - CHAP M1 - Book, Section TI - Fox-Fordyce Disease A1 - Perng, Powell A1 - Sander, Inbal A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEA rare, itchy, chronic papular eruption localized to apocrine gland–bearing areas of the body with unclear etiology.Females are disproportionately affected compared to males (9:1), with age of onset most commonly between 13-35 years of age.Hyperkeratotic plugging of the follicular infundibulum at the apocrine gland duct insertion site is thought to be the primary pathophysiologic event, leading to duct dilation, rupture, inflammation, and pruritus.No definitive cure; oral antihistamines and topical clindamycin may help alleviate symptoms and induce remission. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161325686 ER -