TY - CHAP M1 - Book, Section TI - Rosacea A1 - Steinhoff, Martin A1 - Buddenkotte, Jörg A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCERosacea is a common facial skin disease in many countries.Signs and symptoms for rosacea include flushing, transient erythema, persistent erythema, telangiectasia, papules, pustules, phymata, edema, pain, stinging or burning, and (very rarely) pruritus.The pathophysiology of rosacea is poorly understood; however, a genetic predisposition along with trigger factors activate a dysregulated neurovascular, innate immune, and adaptive immune system.Taking a thorough family and patient history and performing a clinical examination are crucial to diagnose rosacea.All clinical features have to be considered with severity scores for a proper treatment, combined with assessing patient’s quality of life.Approved topical or systemic drugs exist for various, but not all, features of rosacea and should be used on the basis of pathophysiology and while considering efficacy and side effect profiles.Knowledge about the beneficial use of physical therapies and their limitations is important for best medical practice in patients with rosacea.Education about disease progress, general skin care, cosmetic usage and medication effects and potential adverse events is mandatory; teaching of proper topical use guarantees better treatment results.Education to prevent exacerbating “trigger factors” is critical for successful management of patients with rosacea. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161325424 ER -