TY - CHAP M1 - Book, Section TI - Anesthesia for Patients with Neurological & Psychiatric Diseases A1 - Butterworth IV, John F. A1 - Mackey, David C. A1 - Wasnick, John D. PY - 2018 T2 - Morgan & Mikhail's Clinical Anesthesiology, 6e AB - KEY CONCEPTS Induction of anesthesia in patients receiving long-term levodopa therapy may result in either marked hypotension or hypertension. In patients with multiple sclerosis, increases in body temperature cause exacerbation of symptoms. The major risk of anesthesia in patients with autonomic dysfunction is severe hypotension, compromising cerebral and coronary blood flow. Autonomic hyperreflexia should be expected in patients with spinal cord lesions above T6 and can be precipitated by surgical manipulations. The most important interaction between anesthetic agents and tricyclic antidepressants is an exaggerated response to both indirect-acting vasopressors and sympathetic stimulation. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161429642 ER -