TY - CHAP M1 - Book, Section TI - Influenza A1 - Wright, Peter F. A2 - Jameson, J. Larry A2 - Fauci, Anthony S. A2 - Kasper, Dennis L. A2 - Hauser, Stephen L. A2 - Longo, Dan L. A2 - Loscalzo, Joseph PY - 2018 T2 - Harrison's Principles of Internal Medicine, 20e AB - The term influenza represents both a clinically defined respiratory illness accompanied by systemic symptoms of fever, malaise, and myalgia and the name of the orthomyxoviruses that cause this syndrome. Although this term is sometimes used more generally to denote any viral respiratory illness, many features distinguish influenza from these other illnesses, most particularly its systemic symptoms, its propensity to cause sharply peaked winter epidemics, and its capacity to spread rapidly among close contacts. The morbidity and mortality associated with influenza epidemics are documented closely in the United States by the Centers for Disease Control and Prevention (CDC), which records clinical cases of influenza-like illness, cases of virologically documented influenza, and excess deaths due to pneumonia and influenza combined. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1159155079 ER -