TY  - CHAP
M1  - Book, Section
TI  - Endocrine Disorders
A1  - Bartz, Sarah
A1  - Barker, Jennifer M.
A1  - Kappy, Michael S.
A1  - Kelsey, Megan Moriarty
A1  - Travers, Sharon H.
A1  - Zeitler, Philip S.
A2  - Hay, Jr., William W.
A2  - Levin, Myron J.
A2  - Deterding, Robin R.
A2  - Abzug, Mark J.
PY  - 2018
T2  - Current Diagnosis & Treatment: Pediatrics, 24e
AB  - The  classic  concept  that  endocrine  effects  are  the  result  of  substances  secreted  into  the  blood  with  effects  on  a  distant  target  cell  has  been  updated  to  account  for  other  ways  in  which  hormonal  effects  occur.  Specifically,  some  hormone  systems  involve  the  stimulation  or  inhibition  of  metabolic  processes  in  neighboring  cells  (eg,  within  the  pancreatic  islets  or  cartilage).  This  phenomenon  is  termed  paracrine.  Other  hormone  effects  reflect  the  action  of  hormones  on  the  same  cells  that  produced  them.  This  action  is  termed  autocrine.  The  discoveries  of  local  production  of  ghrelin,  somatostatin,  cholecystokinin,  incretins,  and  many  other  hormones  in  the  brain  and  gut  support  the  concept  of  paracrine  and  autocrine  processes  in  these  tissues.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2022/05/23
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1153314380
ER  -