TY - CHAP M1 - Book, Section TI - Vasculitides A1 - Regunathan-Shenk, Renu A1 - Radhakrishnan, Jai A2 - Lerma, Edgar V. A2 - Rosner, Mitchell H. A2 - Perazella, Mark A. PY - 2017 T2 - CURRENT Diagnosis & Treatment: Nephrology & Hypertension, 2e AB - ESSENTIALS OF DIAGNOSISVasculitides affecting the kidneys are typically associated with hematuria and proteinuria, frequently presenting as a rapidly progressive glomerulonephritis.Glomerular injury occurs in the setting of the small vessel vasculitides, associated with antineutrophil cytoplasmic autoantibodies (ANCA), antiglomerular basement membrane antibodies (anti-GBM), or the presence of immune complex formation such as with Henoch–Schönlein purpura (HSP), cryoglobulinemic vasculitis, and systemic lupus erythematosus (SLE).They may affect the kidneys alone, but are more frequently part of a multiorgan disease that may affect the skin, upper and lower respiratory tracts, and the musculoskeletal, gastrointestinal, and nervous systems. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/25 UR - accessmedicine.mhmedical.com/content.aspx?aid=1149114342 ER -