TY - CHAP M1 - Book, Section TI - Anti-Glomerular Basement Membrane Disease (Goodpasture Disease) A1 - Rees, Andrew J. A2 - Lerma, Edgar V. A2 - Rosner, Mitchell H. A2 - Perazella, Mark A. PY - 2017 T2 - CURRENT Diagnosis & Treatment: Nephrology & Hypertension, 2e AB - ESSENTIALS OF DIAGNOSISRapidly deteriorating renal function, with or without hemoptysis and pulmonary shadowing on chest radiograph characterizes this entity.Hematuria and proteinuria on urine dipstick and erythrocyte casts and/or dysmorphic erythrocytes are often seen on urine microscopy.Circulating antibodies directed against the glomerular basement membrane (GBM) are sometimes present.Kidney biopsy often demonstrates focal necrotizing glomerulonephritis with linear deposition of immunoglobulin. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1149114136 ER -