TY - CHAP M1 - Book, Section TI - Gastrointestinal Motility and Water Flux, Emesis, and Biliary and Pancreatic Disease A1 - Sharkey, Keith A. A1 - MacNaughton, Wallace K. A2 - Brunton, Laurence L. A2 - Hilal-Dandan, Randa A2 - Knollmann, Björn C. PY - 2017 T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e AB - AbbreviationsACh: acetylcholineANS: autonomic nervous systemAQP: aquaporinCA: carbonic anhydraseCCK: cholecystokininCFTR: cystic fibrosis transmembrane conductance regulatorCTZ: chemoreceptor trigger zoneCYP: cytochrome P450DOR: delta opioid receptorDRA: downregulated in adenomaECG: electrocardiogramENaC: epithelial sodium channelENS: enteric nervous systemFDA: U.S. Food and Drug AdministrationGC: guanyl cyclaseGERD: gastroesophageal reflux diseaseGI: gastrointestinalGLP: glucagon-like peptideGPCR: G protein–coupled receptorHERG: human ether-a-go-go related geneHIV: human immunodeficiency virus5HT: serotonin, 5-hydroxytryptamineIBS: irritable bowel syndromeKOR: kappa opioid receptorMOR: mu opioid receptorNEP: neutral endopeptidaseNHE: Na+-H+ exchangerNK: neurokininNO: nitric oxideNSAID: nonsteroidal anti-inflammatory drugOTC: over the counterPACAP: pituitary adenylyl cyclase–activating peptidePAF: platelet-activating factorPEG: polyethylene glycolQT: ECG intervalSERT: serotonin transporterSGLT: sodium-glucose cotransporterSLC: solute carrier transporterSSRI: selective serotonin reuptake inhibitorSST: somatostatinSTN: solitary tract nucleusTJ: tight junctionTMEM: transmembrane proteinUSP: U.S. PharmacopeiaVIP: vasoactive intestinal peptide SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/06 UR - accessmedicine.mhmedical.com/content.aspx?aid=1162543397 ER -