TY  - CHAP
M1  - Book, Section
TI  - Cirrhosis and Its Complications
A1  - Avila, Patrick
A1  - Grace, Norman D.
A2  - McKean, Sylvia C.
A2  - Ross, John J.
A2  - Dressler, Daniel D.
A2  - Scheurer, Danielle B.
PY  - 2017
T2  - Principles and Practice of Hospital Medicine, 2e
AB  - Cirrhosis  of  the  liver  is  a  chronic  illness  that  progresses  at  a  variable  rate,  dependent  on  the  etiology  and  the  activity  of  the  offending  toxin.  It  is  a  dynamic  process,  which  is  potentially  reversible  in  the  earlier  stages  if  the  offending  agent  is  either  removed  or  modified.  Classically,  cirrhosis  has  been  defined  histologically  as  architecturally  abnormal  nodules  separated  by  bands  of  fibrous  tissue.  The  diagnosis  has  usually  been  based  on  clinical  suspicion,  confirmed  by  radiologic  studies  and  a  liver  biopsy  as  the  gold  standard.  ­However,  sampling  error  on  biopsy  may  lead  to  incorrect  staging  of  the  disease,  where  the  transition  from  severe  fibrosis  to  cirrhosis  is  misinterpreted.  Therefore,  advanced  chronic  liver  disease  has  been  proposed  as  a  more  encompassing  definition  for  the  transitional  stages.  However,  in  this  chapter,  we  will  continue  to  use  cirrhosis  as  the  term  to  characterize  this  entity.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1137616463
ER  -