TY - CHAP M1 - Book, Section TI - Stroke A1 - Kasper, Dennis L. A1 - Fauci, Anthony S. A1 - Hauser, Stephen L. A1 - Longo, Dan L. A1 - Jameson, J. Larry A1 - Loscalzo, Joseph PY - 2016 T2 - Harrison's Manual of Medicine, 19e AB - Sudden onset of a neurologic deficit from a vascular mechanism: ~85% are ischemic; ~15% are primary hemorrhages (subarachnoid [Chap. 18] and intraparenchymal). An ischemic deficit that resolves rapidly without radiologic evidence of an infarction is termed a transient ischemic attack (TIA); 24 h is a commonly used boundary between TIA and stroke, although most TIAs last between 5 and 15 min. Stroke is a leading cause of neurologic disability in adults; 200,000 deaths annually in the United States. Much can be done to limit morbidity and mortality through prevention and acute intervention. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1128782043 ER -