TY - CHAP M1 - Book, Section TI - Respiratory Failure A1 - Kasper, Dennis L. A1 - Fauci, Anthony S. A1 - Hauser, Stephen L. A1 - Longo, Dan L. A1 - Jameson, J. Larry A1 - Loscalzo, Joseph PY - 2016 T2 - Harrison's Manual of Medicine, 19e AB - Respiratory failure is defined as inadequate gas exchange due to malfunction of one or more components of the respiratory system. There are two main types of acute respiratory failure: hypoxemic and hypercarbic. Hypoxemic respiratory failure is defined by arterial O2 saturation <90% while receiving an increased inspired O2 fraction. Acute hypoxemic respiratory failure can result from pneumonia, pulmonary edema (cardiogenic or noncardiogenic), and alveolar hemorrhage. Hypoxemia results from ventilation-perfusion mismatch and intrapulmonary shunting. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1128781974 ER -