TY - CHAP M1 - Book, Section TI - Liver Transplantation A1 - Qamar, Amir A. A2 - Greenberger, Norton J. A2 - Blumberg, Richard S. A2 - Burakoff, Robert PY - 2016 T2 - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e AB - ESSENTIAL CONCEPTSHepatitis C and hepatocellular carcinoma are among the leading indications for liver transplantation in the United States.Thorough medical, psychiatric, and social evaluation is required prior to listing patients for transplantation.The Model for End-Stage Liver Disease (MELD) score is widely used for prioritizing patients on the transplant waiting list.Liver biopsy is needed to confirm the diagnosis of acute rejection, which is common and occurs in up to 60% of patients.Surgical complications generally occur within days to weeks and medical complications months or years later.Biliary strictures and leaks occur in 15% of patients after transplantation.Long-term immunosuppression, with calcineurin inhibitors, is associated with an increased risk of renal failure. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1119991430 ER -