TY  - CHAP
M1  - Book, Section
TI  - Approach to the Patient with Jaundice & Abnormal Liver Tests
A1  - Greenberger, Norton J.
A2  - Greenberger, Norton J.
A2  - Blumberg, Richard S.
A2  - Burakoff, Robert
PY  - 2016
T2  - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e
AB  - ESSENTIALS  OF  DIAGNOSISJaundice  is  most  often  caused  by  decompensation  of  preexisting  chronic  liver  disease,  alcoholic  hepatitis,  and  gallstone  disease.Careful  history,  physical  examination,  and  routine  laboratory  tests  lead  to  accurate  diagnosis  in  85%  of  patients  with  jaundice.Cirrhosis  can  be  diagnosed  on  the  basis  of  two  physical  findings  (asterixis,  ascites)  and  two  laboratory  findings  (decreased  serum  albumin  [1.6]).Dilated  intrahepatic  bile  ducts  indicate  obstruction  from  extrahepatic  causes  (stone,  structure,  tumor).Absence  of  dilated  ducts  in  jaundiced  patients  with  serum  bilirubin  >10  mg/dL  suggests  intrahepatic  cholestasis.Sepsis,  drugs,  sickle  cell  disease,  and  chronic  hepatitis  are  the  most  common  causes  of  intrahepatic  cholestasis.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1119989810
ER  -