TY - CHAP M1 - Book, Section TI - Gastrointestinal Manifestations of Immunodeficiency A1 - Zhu, Zhenglun A2 - Greenberger, Norton J. A2 - Blumberg, Richard S. A2 - Burakoff, Robert PY - 2016 T2 - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e AB - ESSENTIAL CONCEPTSRecurrent infections and diarrhea are the most common gastrointestinal manifestations of immunodeficiency.Some pathogens (eg, Mycobacterium avium complex) are unique to immunocompromised hosts; others (eg, Cryptosporidium, Giardia lamblia) cause self-limited diarrhea in healthy hosts but chronic diarrhea in immunosuppressed patients.In patients without a specific diagnosis after routine study, endoscopic evaluation with biopsy is important in establishing the diagnosis.Candida species, herpes simplex virus (HSV), cytomegalovirus (CMV), and Mycobacterium species are the most frequent causative agents of infectious esophagitis in an immunocompromised host.In immunocompromised patients, opportunistic infections are a major cause of abdominal pain and can evolve rapidly.The frequency of intestinal lymphomas is increased in patient with common variable immunodeficiency (Chua et al 2008). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/25 UR - accessmedicine.mhmedical.com/content.aspx?aid=1119986477 ER -