TY  - CHAP
M1  - Book, Section
TI  - Infections Acquired in Health Care Facilities
A1  - Weinstein, Robert A.
A2  - Kasper, Dennis
A2  - Fauci, Anthony
A2  - Hauser, Stephen
A2  - Longo, Dan
A2  - Jameson, J. Larry
A2  - Loscalzo, Joseph
Y1  - 2014
N1  - 
T2  - Harrison's Principles of Internal Medicine, 19e
AB  - The  costs  of  hospital-acquired  (nosocomial)  and  other  health  care–associated  infections  are  great.  These  infections  have  affected  as  many  as  1.7  million  patients  at  a  cost  of  ~$28–33  billion  and  99,000  lives  in  U.S.  hospitals  annually.  Although  efforts  to  lower  infection  risks  have  been  challenged  by  the  numbers  of  immunocompromised  patients,  antibiotic-resistant  bacteria,  fungal  and  viral  superinfections,  and  invasive  devices  and  procedures,  a  prevailing  viewpoint—often  termed  “zero  tolerance”—is  that  almost  all  health  care–associated  infections  should  be  avoidable  with  strict  application  of  evidence-based  prevention  guidelines  (Table  168-1).  In  fact,  rates  of  device-related  infections—historically,  the  largest  drivers  of  risk—have  fallen  steadily  over  the  past  few  years.  Unfortunately,  at  the  same  time,  antimicrobial-resistant  pathogens  have  risen  in  number  and  are  estimated  to  contribute  to  ~23,000  deaths  in  and  outside  of  hospitals  annually.  This  chapter  reviews  health  care–associated  and  device-related  infections  as  well  as  basic  surveillance,  prevention,  control,  and  treatment  activities.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2021/04/10
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1120797274
ER  -