TY  - CHAP
M1  - Book, Section
TI  - Respiratory System Response to Exercise in Health
A1  - Dempsey, Jerome A.
A1  - Jacques, Anthony J.
A2  - Grippi, Michael A.
A2  - Elias, Jack A.
A2  - Fishman, Jay A.
A2  - Kotloff, Robert M.
A2  - Pack, Allan I.
A2  - Senior, Robert M.
A2  - Siegel, Mark D.
Y1  - 2015
N1  - 
T2  - Fishman's Pulmonary Diseases and Disorders, 5e
AB  - The  increases  in  muscular  oxygen  consumption  (V̇O2)  and  carbon  dioxide  production  (V̇CO2)  accompanying  whole-body  exercise  present  a  greater  challenge  to  the  maintenance  of  pulmonary  gas  exchange  than  any  other  physiologic  stressor.  This  chapter  discusses  the  responses  of  the  healthy  respiratory  system  to  exercise  with  an  emphasis  on  the  following  problems:  what  neurochemical  mechanisms  regulate  the  ventilatory  response  to  exercise  and  what  are  the  consequences  of  this  hyperpnea  to  the  work  and  to  the  fatigue  of  the  respiratory  muscles?  What  mechanisms  underlie  the  widening  of  the  alveolar  to  arterial  partial  pressure  of  oxygen  (Po2)  difference  during  exercise?  How  do  the  unique  characteristics  of  the  pulmonary  circulation  determine  its  response  to  exercise?  How  does  respiration  impact  the  cardiovascular  response  to  exercise?  Under  what  circumstances  might  the  respiratory  system  provide  a  limitation  to  O2  transport  and/or  exercise  performance?  We  consider  these  problems  primarily  in  the  healthy,  young,  normally  fit  adult,  with  reference  to  special  cases  of  the  highly  trained  athlete  and  to  the  effects  of  healthy  aging,  high  altitude  hypoxia,  and  physical  training.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/24
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1122355615
ER  -