TY - CHAP M1 - Book, Section TI - Thalassemia A1 - Bunn, H. Franklin A1 - Nathan, David G. A2 - Bunn, H. Franklin A2 - Aster, Jon C. Y1 - 2011 N1 - T2 - Pathophysiology of Blood Disorders AB - LEARNING OBJECTIVESAfter studying this chapter you should be able to:Outline the changes in globin gene expression that occur during fetal development.Explain the molecular genetics and inheritance of alpha and beta thalassemias.Grasp the cellular pathogenesis of alpha and beta thalassemias.Describe the clinical and laboratory features of beta thalassemia minor (trait) and beta thalassemia major and the different types of alpha thalassemia.Understand the pathophysiologic principles underlying treatment of beta thalassemia major. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1104131083 ER -