TY - CHAP M1 - Book, Section TI - Arrhythmogenic Right Ventricular Cardiomyopathy A1 - Barnes, Carl A1 - Taylor, Matthew RG A2 - Murray, Michael F. A2 - Babyatsky, Mark W. A2 - Giovanni, Monica A. A2 - Alkuraya, Fowzan S. A2 - Stewart, Douglas R. Y1 - 2014 N1 - T2 - Clinical Genomics: Practical Applications in Adult Patient Care AB - Disease summary:Arrhythmogenic right ventricular cardiomyopathy (ARVC), formerly referred to as arrhythmogenic right ventricular dysplasia (ARVD), is a heart muscle disease predominantly affecting the right ventricle.Pathologically, the central feature is a progressive replacement of right ventricular myocardium with fibrofatty tissue.Clinically, affected individuals present with palpitations, syncope, or sudden death as a result of ventricular arrhythmias, such as ventricular tachycardia or fibrillation, with symptomatic heart failure usually only in later stages.While the majority of patients do not present with sudden cardiac death, ARVC may account for 10% to 20% of sudden cardiac death in individuals younger than age 35.The prevalence of ARVC is estimated to be 1 case per 1000 to 5000 of the general population. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/04 UR - accessmedicine.mhmedical.com/content.aspx?aid=1102699245 ER -