TY  - CHAP
M1  - Book, Section
TI  - The Preterm Newborn
A1  - Cunningham, F. Gary
A1  - Leveno, Kenneth J.
A1  - Bloom, Steven L.
A1  - Spong, Catherine Y.
A1  - Dashe, Jodi S.
A1  - Hoffman, Barbara L.
A1  - Casey, Brian M.
A1  - Sheffield, Jeanne S.
Y1  - 2013
N1  - 
T2  - Williams Obstetrics, 24e
AB  - The  preterm  infant  is  susceptible  to  various  serious  medical  complications  during  the  newborn  period  as  well  as  morbidities  extending  later  into  life  (Table  34-1).  These  complications  are  primarily  the  consequence  of  immature  organs  that  result  from  abbreviated  gestation.  A  less  commonly  cited  cause  of  morbidity  and  mortality  is  congenital  malformations,  which  are  much  more  prevalent  in  preterm  births.  For  example,  between  2010  and  2013  at  Parkland  Hospital,  major  malformations  were  diagnosed  in  67  per  1000  singleton  births  <  37  weeks’  gestation.  This  compared  with  15  per  1000  in  those  ≥  38  weeks—an  almost  fivefold  excess.  The  pivotal  complication,  however,  is  respiratory  distress  syndrome  (RDS).  This  results  from  immature  lungs  that  are  unable  to  sustain  necessary  oxygenation.  Resulting  hypoxia  is  an  underlying  associated  cause  of  neurological  damage  such  as  cerebral  palsy.  In  addition,  hyperoxia,  a  side  effect  of  RDS  treatment,  causes  bronchopulmonary  dysplasia  and  retinopathy  of  prematurity.  These  complications  of  prematurity  can  be  placed  in  perspective  in  terms  of  the  human  consequences.  In  2009,  two  thirds  of  all  infant  deaths  in  the  United  States  were  in  the  12  percent  of  infants  who  were  born  <  37  weeks  (Mathews,  2013).  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2022/05/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1102104308
ER  -