TY - CHAP M1 - Book, Section TI - Anemia A1 - Vanasse, Gary J. A2 - Williams, Brie A. A2 - Chang, Anna A2 - Ahalt, Cyrus A2 - Chen, Helen A2 - Conant, Rebecca A2 - Landefeld, C. Seth A2 - Ritchie, Christine A2 - Yukawa, Michi Y1 - 2014 N1 - T2 - Current Diagnosis & Treatment: Geriatrics, 2e AB - Anemia is a common condition in older adults and is an increasingly recognized contributor to increased morbidity and mortality. Similar to the younger adult anemic patient, anemia in older adults is most commonly defined according to the 1968 World Health Organization (WHO) criteria of a hemoglobin (Hgb) <13 g/dL in men and <12 g/dL in women. Although anemia has often been considered a normal consequence of aging, its association with adverse clinical outcomes merits a thorough evaluation into the underlying pathophysiology. Recent studies suggest that anemia may arise as a result of accumulated effects of age-related comorbidities acting in concert with poorly understood age-specific changes in early hematopoietic progenitors, that combine to influence erythrocyte production. A greater understanding of the pathogenesis of anemia in older adults will likely have important implications for the prevention, diagnosis, and therapy of this common problem. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessmedicine.mhmedical.com/content.aspx?aid=1100068320 ER -