TY - CHAP M1 - Book, Section TI - Chapter 31. Takayasu Arteritis A1 - Hellmann, David B. A2 - Imboden, John B. A2 - Hellmann, David B. A2 - Stone, John H. Y1 - 2013 N1 - T2 - CURRENT Diagnosis & Treatment: Rheumatology, 3e AB - Takayasu arteritis, named for the Japanese ophthalmologist who first described the ocular manifestations in 1908, is a large-vessel vasculitis of unknown cause that chiefly affects women during their reproductive years. The disease often presents two challenges. First, the diagnosis can be delayed for months or even years due to the rarity of the disease, the young age of the (typical) patient, and the protean presenting manifestations. Second, treatment is a challenge. Although Takayasu arteritis is a chronic disease, it usually pursues a waxing and waning course that requires careful monitoring to determine when the disease is active and medical therapy is needed. Treatment with glucocorticoids usually succeeds in halting progression of the vasculitis. Indeed, because of the advances in medical therapy and surgical treatment of vascular complications, such as aortic regurgitation, survival of patients with Takayasu arteritis has increased dramatically. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=57273118 ER -