TY  - CHAP
M1  - Book, Section
TI  - Chapter 60. Dextromethorphan
A1  - Anderson, Ilene B.
A2  - Olson, Kent R.
Y1  - 2012
N1  - 
T2  - Poisoning & Drug Overdose, 6e
AB  - Dextromethorphan  is  a  common  antitussive  agent  found  in  many  over-the-counter  cough  and  cold  preparations.  Dextromethorphan  is  often  found  in  combination  products  containing  antihistamines  (See  Antihistamines),  decongestants  (See  Pseudoephedrine,  Phenylephrine,  and  Other  Decongestants),  ethanol  (See  Ethanol),  or  acetaminophen  (See  Acetaminophen).  Common  combination  products  containing  dextromethorphan  include  Coricidin  HBP  Cough  &  Cold  Tablets,  Robitussin  DM,  and  NyQuil  Nighttime  Cold  Medicine.  Dextromethorphan  is  well  tolerated  at  therapeutic  doses,  and  serious  toxicity  rarely  occurs,  even  with  moderate  to  high  doses.  However,  major  toxicity  and  death  have  been  reported,  caused  either  by  dextromethorphan  as  a  sole  agent  or  more  commonly  by  co-ingestants,  drug-drug  interactions,  or  genetic  polymorphism.  Intentional  abuse,  especially  among  adolescents  and  young  adults,  has  been  a  rising  problem  owing  to  the  hallucinogenic  potential  at  high  doses.  Common  slang  terms  include  “triple  C,”  “CCC,”  “skittles,”  “robo,”  “DXM,”  and  “dex.”  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2021/04/18
UR  - accessmedicine.mhmedical.com/content.aspx?aid=55976470
ER  -