TY - CHAP M1 - Book, Section TI - Chapter 60. Dextromethorphan A1 - Anderson, Ilene B. A2 - Olson, Kent R. Y1 - 2012 N1 - T2 - Poisoning & Drug Overdose, 6e AB - Dextromethorphan is a common antitussive agent found in many over-the-counter cough and cold preparations. Dextromethorphan is often found in combination products containing antihistamines (See Antihistamines), decongestants (See Pseudoephedrine, Phenylephrine, and Other Decongestants), ethanol (See Ethanol), or acetaminophen (See Acetaminophen). Common combination products containing dextromethorphan include Coricidin HBP Cough & Cold Tablets, Robitussin DM, and NyQuil Nighttime Cold Medicine. Dextromethorphan is well tolerated at therapeutic doses, and serious toxicity rarely occurs, even with moderate to high doses. However, major toxicity and death have been reported, caused either by dextromethorphan as a sole agent or more commonly by co-ingestants, drug-drug interactions, or genetic polymorphism. Intentional abuse, especially among adolescents and young adults, has been a rising problem owing to the hallucinogenic potential at high doses. Common slang terms include “triple C,” “CCC,” “skittles,” “robo,” “DXM,” and “dex.” SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2022/08/14 UR - accessmedicine.mhmedical.com/content.aspx?aid=55976470 ER -