TY - CHAP M1 - Book, Section TI - Chapter 237. Phototherapy A1 - Cafardi, Jennifer A. A1 - Pollack, Brian P. A1 - Elmets, Craig A. A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintPhototherapy at a GlancePhototherapeutic devices have varying properties with respect to depth of UV penetration into the skin, effects on cells and molecules, potency, side effects and diseases in which they are most effective.In use today are narrowband and broadband UVB, UVA as part of psoralen photochemotherapy (PUVA), UVA1 and targeted phototherapy (excimer lasers and nonlaser monochromatic excimer light sources).Narrowband UVB is currently preferred to treat psoriasis, other inflammatory skin diseases, and vitiligo.Psoralen-UVA photochemotherapy (PUVA) combines oral or topical psoralen compounds with UVA light sources. Its main uses are treatment of cutaneous T-cell lymphoma, vitiligo, and psoriasis that is resistant to narrowband UVB.UVA1 phototherapy is particularly effective for sclerotic skin diseases such as localized scleroderma, acute flares of atopic dermatitis and urticaria pigmentosa.Targeted phototherapy allowing relatively high UV doses to be delivered to diseased skin while sparing normal skin. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=56103273 ER -