TY - CHAP M1 - Book, Section TI - Chapter 229. Antihistamines A1 - Wood, Robert A. A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintAntihistamines at a GlanceH1 are first-line therapy for chronic idiopathic and physical urticarias.H1 may be useful in treating other conditions with histamine-driven pruritus.Limited evidence supports the use of H1 in treatment of atopic dermatitis.Certain special patient populations, including children, the elderly, and patients with renal or hepatic impairment, may require dosage adjustments when using H1 antihistamines.The use of H1 is contraindicated in patients who have narrow angle glaucoma or who are also taking monoamine oxidase inhibitors.H2 antihistamines may be a useful adjunct to H1 antihistamine therapy in refractory cases of chronic idiopathic urticaria/angioedema and pruritus. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=56100245 ER -