TY - CHAP M1 - Book, Section TI - Chapter 202. Chancroid A1 - Lautenschlager, Stephan A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintChancroid at a GlanceA sexually transmitted acute ulcerative disease usually localized at the anogenital area and often associated with inguinal adenitis or bubo.Haemophilus ducreyi—a Gram-negative, facultative anaerobic coccobacillus—is the causative agent.Although the number of cases is decreasing overall, chancroid is still common in many developing countries (Africa, the Caribbean Islands, and Southwest Asia).Painful, soft ulcers with ragged undermined margins develop 1–2 weeks after inoculation (usually prepuce and frenulum in men and vulva, cervix, and perianal area in women).Nonsexual transmission has been reported recently.Chancroid facilitates the transmission of HIV.Laboratory culture of H. ducreyi is problematic, but greater sensitivity can be expected by DNA amplification methods, which are currently not routinely available.Azithromycin and Ceftriaxone are recommended as single-dose treatment, enhancing compliance. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/23 UR - accessmedicine.mhmedical.com/content.aspx?aid=56091426 ER -