TY - CHAP M1 - Book, Section TI - Chapter 145. Cutaneous Lymphoma A1 - Beyer, Marc A1 - Sterry, Wolfram A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintCutaneous Lymphoma at a GlanceSecond most common group of extranodal lymphomas; estimated annual incidence is 1 in 100,000.Clonal proliferations of neoplastic T or B lymphocytes, and rarely of natural killer cells or plasmacytoid dendritic cells, arising in mid and late adulthood.Clinical behavior and prognosis are completely different from those of histologically similar systemic lymphomas.Most common form of cutaneous lymphoma is mycosis fungoides (MF), a cutaneous T-cell lymphoma, which is categorized as patch, plaque, or tumor stage. Related features include severe pruritus, alopecia, palmoplantar hyperkeratosis, and bacterial superinfectionHistologically the patch/plaque stage of MF is characterized by an epidermotropic band-like infiltrate of neoplastic T lymphocytes with hyperconvoluted cerebriform nuclei involving the upper dermis variably with exocytosis and formation of intraepidermal Pautrier's microabscesses. The tumor stage consists of a dermal nodular infiltrate sparing the epidermis. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=56071898 ER -