TY - CHAP M1 - Book, Section TI - Chapter 128. Kaposi's Sarcoma and Angiosarcoma A1 - Tschachler, Erwin A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintKaposi's Sarcoma at a GlanceMultifocal tumor of endothelial cell origin with stage-dependent characteristic histopathology.Occurs in four clinical variants:Classical Kaposi's sarcoma (KS)—in old men; starts as localized form; progresses slowly.Endemic African KS—most frequent neoplasm in some Central African countries; also includes a rapidly progressive lymphadenopathic variant.KS associated with immunosuppressive therapy—most frequently in organ-transplant recipients.AIDS-related KS—rapidly progressive form in HIV-infected patients with early involvement of extracutaneous sites.KS development is invariably linked with human herpesvirus (HHV)-8 infection.Despite presumed viral pathogenesis, KS responds well to chemotherapy and radiation therapy. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/16 UR - accessmedicine.mhmedical.com/content.aspx?aid=56064106 ER -