TY - CHAP M1 - Book, Section TI - Chapter 127. Neoplasias and Hyperplasias of Muscular and Neural Origin A1 - White, Lucile E. A1 - Levy, Ross M. A1 - Alam, Murad A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - The dermis contains smooth muscle fibers in the arrector pili muscles, in the walls of dermal blood vessels, and in the dartos muscle of the scrotum, vulva, nipple, and areola. There are three types of cutaneous smooth muscle lesions: (1) leiomyomas, (2) leiomyosarcomas, and (3) hamartomas. Smooth muscle is recognized histologically by spindle cell shape, eosinophilic, fibrillary cytoplasm, and blunt-ended, oval, “cigar-shaped” nuclei. On immunohistochemical staining, cells express smooth muscle actin and the muscle-specific intermediate filament desmin, but are negative for S100 protein and epithelial membrane antigen (EMA). SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=56063652 ER -