TY - CHAP M1 - Book, Section TI - Chapter 25. Parapsoriasis and Pityriasis Lichenoides A1 - Wood, Gary S. A1 - Hu, Chung-Hong A1 - Liu, Rosemarie A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintParapsoriasis at a GlanceAlso known as parapsoriasis en plaques.Parapsoriasis occurs worldwide and affects mainly adults.Large-plaque parapsoriasis (LPP) and small-plaque parapsoriasis (SPP) are recognized.Large and small “plaque” lesions actually present as flat patches rather than infiltrated plaques.Lesions are chronic and favor nonsun-exposed skin; LPP may be poikilodermatous.Pathology consists of superficial, mostly CD4+ T-cell infiltrate; dominant clonality is more common in LPP than in SPP.LPP appears to exist on a continuum with patch-stage mycosis fungoides (MF) and progresses to overt MF at a rate of approximately 10% per decade.SPP has minimal risk of progression to overt MF in the experience of most experts.Treatment options include topical corticosteroids; ultraviolet B (UVB) irradiation, and psoralen and ultraviolet A (UVA) irradiation; excimer laser; and topical cytotoxic drugs. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/17 UR - accessmedicine.mhmedical.com/content.aspx?aid=56028115 ER -