TY - CHAP M1 - Book, Section TI - Chapter 10. Innate and Adaptive Immunity in the Skin A1 - Modlin, Robert L. A1 - Miller, Lloyd S. A1 - Bangert, Christine A1 - Stingl, Georg A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintInnate and Adaptive Immunity at a GlanceInnate immune responses are used by the host to immediately defend itself;determine the quality and quantity of many adaptive immune responses;are short lived;have no memory;include physical barriers (skin and mucosal epithelia);include soluble factors such as complement, antimicrobial peptides, chemokines, and cytokines;include cells such as monocytes/macrophages, dendritic cells, natural killer cells, and polymorphonuclear leukocytes.Adaptive immune responses have memory;have specificity;are long lasting;in skin, are initiated by dendritic antigen-presenting cells in the epidermis (Langerhans cells) and by dermal dendritic cells;are executed by T lymphocytes and antibodies produced by B lymphocytes/plasma cells. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=56022615 ER -