TY - CHAP M1 - Book, Section TI - Chapter 52. Continuous Renal Replacement Therapy A1 - Liu, Frank A1 - Mehta, Ravindra A2 - Lerma, Edgar V. A2 - Berns, Jeffrey S. A2 - Nissenson, Allen R. Y1 - 2009 N1 - T2 - CURRENT Diagnosis & Treatment: Nephrology & Hypertension AB - Continuous renal replacement therapy (CRRT) represents a number of technically distinct modalities characterized by slow per-minute solute clearance and ultrafiltration rates that are spread over most or all of the day to minimize wide metabolic or volume shifts. Continuous techniques were originally described in the 1970s as experimental treatment for diuretic-resistant, hypervolemic patients whose clinical picture made them inappropriate candidates for either peritoneal dialysis (PD) or intermittent hemodialysis (IHD). Since then, the presence of CRRT in the intensive care unit (ICU) has evolved both in scope and complexity, and as a result, CRRT techniques are quickly becoming the standard of care for critically ill patients with acute renal failure (ARF). This chapter will review the major terms used in the delivery of CRRT, the most prominent clinical and technical issues encountered by the healthcare teams, and promising technologies that may improve the efficacy and future applicability of the relevant modalities. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=6340650 ER -