TY - CHAP M1 - Book, Section TI - Chapter 4. Genital Ulcer Disease A1 - Cohen, Daniel E. A1 - Mayer, Kenneth A2 - Klausner, Jeffrey D. A2 - Hook, Edward W. Y1 - 2007 N1 - T2 - CURRENT Diagnosis & Treatment of Sexually Transmitted Diseases AB - • Diagnosis is based on the finding of one or more mucocutaneous ulcers involving the genitalia, perineum, or anus.• Careful inspection of all genital mucosa is important, as lesions may be inside the foreskin, labia, vagina, or rectum, and may be painless.• Genital herpes is the most common cause, followed by syphilis.• A specific pathogen often cannot be identified based on clinical findings alone; laboratory testing should include culture or polymerase chain reaction (PCR) amplification for herpes simplex virus (HSV), and serologic testing for syphilis.• Despite appropriate testing, no pathogen is identified in up to 50% of patients. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=3026959 ER -