TY  - CHAP
M1  - Book, Section
TI  - Chapter 19. Long-Term Outcomes of Critical Illness
A1  - Herridge, Margaret S.
A1  - Hopkins, Ramona O.
A2  - Hall, Jesse B.
A2  - Schmidt, Gregory A.
A2  - Wood, Lawrence D.H.
Y1  - 2005
N1  - 
T2  - Principles of Critical Care, 3e
AB  - Survivors  of  critical  illness  experience  decreased  health-related  quality  of  life  due  to  physical  limitations,  depression  and  anxiety,  and  cognitive  impairments.There  may  be  irreversible  long-term  neuromuscular  dysfunction  (e.g.,  muscle  weakness,  critical  illness  polyneuropathy,  and  myopathy).Other  organ  dysfunction  (e.g.,  pulmonary)  is  present  following  critical  illness  but  does  not  appear  to  have  the  same  impact  on  patients'  self-reported  quality-of-life  outcomes  as  other  morbidities.Hypoxia  and  delirium  are  risk  factors  for  poor  long-term  outcome  resulting  from  cognitive  impairments.Approximately  one-third  to  one-half  of  survivors  of  critical  illness  will  develop  long-term  cognitive  impairments.Recent  reports  suggest  that  exercise  capacity  and  cognitive  function  plateau  at  a  lower  than  normal  level  at  1  year  with  limited  improvement  2  years  following  ICU  discharge.Long-term  physical  and  neuropsychological  dysfunction  may  be  remediable  through  the  implementation  of  a  multidisciplinary  and  family-centered  rehabilitation  program.  This  is  currently  being  evaluated.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2022/08/08
UR  - accessmedicine.mhmedical.com/content.aspx?aid=2283969
ER  -