TY - CHAP M1 - Book, Section TI - Chapter 14. Eosinophilic Esophagitis A1 - Greenberger, Norton J. A2 - Greenberger, Norton J. A2 - Blumberg, Richard S. A2 - Burakoff, Robert Y1 - 2012 N1 - T2 - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e AB - In adults, a major symptom is recurrent dysphagia, often with food impaction; mean duration of symptoms before treatment is 4–6 years.Esophageal biopsy shows dense eosinophilic infiltration (≥20 eosinophils per high power field [HPF]).Full diagnostic criteria are (1) clinical symptoms of esophageal dysfunction; (2) increased eosinophils in esophageal mucosal biopsies; (3) lack of sustained response to high-dose proton pump inhibition treatment or normal pH monitoring of the distal esophagus. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=55956994 ER -