TY  - CHAP
M1  - Book, Section
TI  - Fluid, Electrolyte, & Acid–Base Disorders & Therapy
A1  - Hanna, Melisha G.
A1  - Bock, Margret E.
A2  - Bunik, Maya
A2  - Levin, Myron J.
A2  - Abzug, Mark J.
A2  - Schreiner, Teri L.
Y1  - 2025
N1  - 
T2  - Current Diagnosis &amp; Treatment: Pediatrics, 27<sup>th</sup> Edition
AB  - Total  body  water  (TBW)  constitutes  50%–75%  of  the  total  body  mass,  depending  on  age,  sex,  and  fat  content.  After  an  initial  brisk  postnatal  diuresis,  the  TBW  slowly  decreases  to  the  adult  range  near  puberty.  Values  vary  with  differing  amounts  of  body  fat;  muscle  has  higher  water  content  than  fat.  TBW,  for  example,  decreases  with  increasing  obesity.  TBW  is  divided  into  the  intracellular  and  extracellular  spaces,  separated  by  cell  membranes  (Figure  23–1).  Intracellular  fluid  (ICF)  accounts  for  two-thirds  of  the  TBW  and  extracellular  fluid  (ECF)  for  one-third.  The  ECF  is  further  compartmentalized  into  plasma  (intravascular)  volume  and  interstitial  fluid  (ISF).  Size  of  ECF  components  vary  by  age—being  larger  in  infants  and  young  children.  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2025/03/21
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1211982007
ER  -