TY  - CHAP
M1  - Book, Section
TI  - Neutrophil-Mediated Diseases
A1  - Saavedra, Arturo P.
A1  - Roh, Ellen K.
A1  - Mikailov, Anar
Y1  - 2023
N1  - 
T2  - Fitzpatrick’s Color Atlas and Synopsis of Clinical Dermatology, 9e
AB  - PG  is  an  idiopathic,  either  acute  or  chronic,  severely  debilitating  skin  disease.It  is  characterized  by  neutrophilic  infiltration,  destruction  of  tissue,  and  ulceration.It  occurs  most  commonly  in  association  with  a  systemic  disease,  especially  arthritis,  inflammatory  bowel  disease,  hematologic  dyscrasias,  and  malignancy,  but  may  also  occur  alone.Characterized  by  the  presence  of  painful,  irregular,  boggy,  blue–red  ulcers  with  undermined  borders  and  purulent  necrotic  bases.It  is  a  diagnosis  of  exclusion.The  mainstays  of  treatment  are  immunosuppressive  or  immunomodulating  agents.Relapses  occur  in  most  patients  and  there  is  significant  morbidity.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/23
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1199569049
ER  -