TY - CHAP M1 - Book, Section TI - Changes in the Cardiorespiratory System During Sleep A1 - Gurubhagavatula, Indira A1 - Patil, Susheel P. A2 - Grippi, Michael A. A2 - Antin-Ozerkis, Danielle E. A2 - Dela Cruz, Charles S. A2 - Kotloff, Robert M. A2 - Kotton, Camille Nelson A2 - Pack, Allan I. Y1 - 2023 N1 - T2 - Fishman’s Pulmonary Diseases and Disorders, 6e AB - As outlined in Chapter 12, sleep occurs in distinct states classified broadly as non–rapid eye movement (NREM) sleep and rapid eye movement (REM) sleep. These states occur in a temporally organized fashion across the sleep period, with NREM dominating during the initial hours of sleep and REM during the later hours of sleep. REM sleep cycles occur in 90- to 120-min cycles, with a typical healthy adult experiencing 3 to 5 cycles during the major sleep bout. Specific alterations in autonomic regulation occur during REM sleep, which may at least partly explain the higher frequency of occurrence of myocardial infarction and ischemic stroke during early morning hours,1–3 when REM sleep predominates. This chapter presents additional information on alterations in cardiopulmonary function during sleep. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1195011817 ER -