TY - CHAP M1 - Book, Section TI - Pulmonary Vasculitis A1 - Cartin-Ceba, Rodrigo A1 - Specks, Ulrich A2 - Grippi, Michael A. A2 - Antin-Ozerkis, Danielle E. A2 - Dela Cruz, Charles S. A2 - Kotloff, Robert M. A2 - Kotton, Camille Nelson A2 - Pack, Allan I. Y1 - 2023 N1 - T2 - Fishman’s Pulmonary Diseases and Disorders, 6e AB - Pulmonary vasculitis is usually a manifestation of a systemic disorder leading to inflammation of vessels of different sizes by a variety of immunologic mechanisms. Vasculitis can be separated into primary and secondary vasculitis. The primary systemic vasculitides are a heterogeneous group of syndromes of unknown etiology, which share a clinical response to immunosuppressive therapy (Table 74-1). Their wide spectrum of frequently overlapping clinical manifestations is defined by the size and location of the affected vessels as well as the nature of the inflammatory infiltrate. Secondary vasculitis may pose significant management problems in the context of a well-defined underlying disorder, such as diffuse alveolar hemorrhage caused by systemic lupus erythematosus. Alternatively, secondary vasculitis may be an incidental histopathologic finding, for instance, in the context of an infection or necrotizing sarcoid granulomatosis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessmedicine.mhmedical.com/content.aspx?aid=1195008389 ER -