TY - CHAP M1 - Book, Section TI - Mast Cells and Eosinophils A1 - Schulman, Edward S. A1 - Sporn, Peter H.S. A1 - Samarasinghe, Amali E. A2 - Grippi, Michael A. A2 - Antin-Ozerkis, Danielle E. A2 - Dela Cruz, Charles S. A2 - Kotloff, Robert M. A2 - Kotton, Camille Nelson A2 - Pack, Allan I. Y1 - 2023 N1 - T2 - Fishman’s Pulmonary Diseases and Disorders, 6e AB - Hematopoietic stem cells that differentiate into common myeloid stem cells give rise to granulocytes that include mast cells (MC), eosinophils, basophils, and neutrophils. In addition to the shared heritage, granulocytes share physical and functional similarities. MCs and eosinophils are popularly known for their presence and function during allergic diseases. Because physicians have noted a clear connection between mast cell activation and the subsequent appearance of eosinophils both within the circulation and in tissues for over a century, MCs and eosinophils are considered together in this chapter. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1194947186 ER -