TY - CHAP M1 - Book, Section TI - Molecular Regulation of Lung Development A1 - Cardoso, Wellington V. A1 - Yang, Ying A1 - Lu, Jining A2 - Grippi, Michael A. A2 - Antin-Ozerkis, Danielle E. A2 - Dela Cruz, Charles S. A2 - Kotloff, Robert M. A2 - Kotton, Camille Nelson A2 - Pack, Allan I. Y1 - 2023 N1 - T2 - Fishman’s Pulmonary Diseases and Disorders, 6e AB - This chapter focuses on the mechanisms that control the development of the respiratory system from specification of the progenitors of the primordial lung to the formation of the definitive alveoli. The respiratory system is characterized not only by its major diversity in cellular phenotypes, but also by its complex 3D architecture in both the airway and alveolar compartments designed to conduct air and facilitate gas exchange. Its network of conduits comprises the trachea and extrapulmonary and intrapulmonary airways formed by multiple generations of branching epithelial tubules. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1194945395 ER -