TY - CHAP M1 - Book, Section TI - Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death A1 - Albert, Christine A1 - H. Sauer, William A2 - Loscalzo, Joseph A2 - Fauci, Anthony A2 - Kasper, Dennis A2 - Hauser, Stephen A2 - Longo, Dan A2 - Jameson, J. Larry Y1 - 2022 N1 - T2 - Harrison's Principles of Internal Medicine, 21e AB - Cardiovascular collapse is severe hypotension from acute cardiac dysfunction or loss of peripheral vasculature resistance resulting in cerebral hypoperfusion and loss of consciousness (See Table 306-1). This condition can be the result of a cardiac arrhythmia, severe myocardial or valvular dysfunction, loss of vascular tone, and/or acute disruption of venous return. When an effective circulation is restored spontaneously, patients present with syncope (see Chap. 21). In the absence of spontaneous resolution, then cardiac arrest occurs, ultimately resulting in death if resuscitation attempts are unsuccessful or not initiated. Underlying etiologies for cardiovascular collapse include benign conditions, such as neurocardiogenic syncope, but also life-threatening conditions including: ventricular tachyarrhythmias; severe bradycardia; severely depressed myocardial contractility, as with massive acute myocardial infarction (MI) or pulmonary embolus; and other catastrophic events interfering with cardiac function such as myocardial rupture with cardiac tamponade or papillary muscle rupture with torrential mitral regurgitation. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/24 UR - accessmedicine.mhmedical.com/content.aspx?aid=1206273952 ER -