TY - CHAP M1 - Book, Section TI - Special Situations in Breast Cancer A1 - Layman, Rachel M. A2 - Kantarjian, Hagop M. A2 - Wolff, Robert A. A2 - Rieber, Alyssa G. Y1 - 2022 N1 - T2 - The MD Anderson Manual of Medical Oncology, 4e AB - KEY CONCEPTSManagement of pregnancy-associated breast cancer requires careful multidisciplinary care and coordination for optimal outcomes.Pregnancy after a breast cancer diagnosis is not associated with worsened outcomes, based on retrospective data.Male breast cancer management is largely extrapolated from data on female breast cancer; however, tamoxifen is the preferred endocrine therapy agent.Combined hormone replacement therapy with estrogen and progesterone in postmenopausal women increases the risk of developing breast cancer, but risk is not clearly increased with estrogen-only therapy.Adjuvant endocrine therapy with tamoxifen or an aromatase inhibitor can be considered for estrogen receptor–positive ductal carcinoma in situ.Patients with pathogenic mutations in breast cancer susceptibility genes should be counseled regarding the risks and benefits of screening and prevention options. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1190836697 ER -