TY  - CHAP
M1  - Book, Section
TI  - Urinary Tract Infections, Pyelonephritis, and Prostatitis
A1  - Gupta, Kalpana
A1  - Trautner, Barbara W.
A2  - Loscalzo, Joseph
A2  - Fauci, Anthony
A2  - Kasper, Dennis
A2  - Hauser, Stephen
A2  - Longo, Dan
A2  - Jameson, J. Larry
Y1  - 2022
N1  - 
T2  - Harrison's Principles of Internal Medicine, 21e
AB  - Urinary  tract  infection  (UTI)  is  a  common  and  painful  human  illness  that  is  rapidly  responsive  to  modern  antibiotic  therapy,  if  the  correct  antibiotic  is  chosen  for  the  particular  urinary  pathogen.  In  the  preantibiotic  era,  UTI  caused  significant  morbidity.  Hippocrates,  writing  about  a  disease  that  appears  to  have  been  acute  cystitis,  said  that  the  illness  could  last  for  a  year  before  either  resolving  or  worsening  to  involve  the  kidneys.  When  chemotherapeutic  agents  used  to  treat  UTI  were  introduced  in  the  early  twentieth  century,  they  were  relatively  ineffective,  and  persistence  of  infection  after  3  weeks  of  therapy  was  common.  Nitrofurantoin,  which  became  available  in  the  1950s,  was  the  first  tolerable  and  effective  agent  for  the  treatment  of  UTI.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1201012844
ER  -