TY - CHAP M1 - Book, Section TI - Infections Acquired in Health Care Facilities A1 - Weinstein, Robert A. A2 - Loscalzo, Joseph A2 - Fauci, Anthony A2 - Kasper, Dennis A2 - Hauser, Stephen A2 - Longo, Dan A2 - Jameson, J. Larry Y1 - 2022 N1 - T2 - Harrison's Principles of Internal Medicine, 21e AB - Health care–associated infections affect at least 2 million patients at a cost of billions of dollars and 100,000 or more lives in U.S. hospitals annually. Guidelines from the Centers for Disease Control and Prevention (CDC) (www.cdc.gov/hicpac/), the Agency for Healthcare Research and Quality (www.ahrq.gov), and professional societies (e.g., www.shea-online.org; www.idsociety.org; www.apic.org; www.his.org.uk) have led to marked reductions in occurrence of most device-related infections (https://www.cdc.gov/hai/data/portal/progress-report.html)—historically, the largest drivers of nosocomial infection risk. Despite these successes, there is the seemingly unending threat of antimicrobial-resistant infections and novel pathogens. This chapter reviews the epidemiology, prevention, and control of health care–associated infections and newer challenges. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1190479711 ER -