TY  - CHAP
M1  - Book, Section
TI  - Cancer Survivorship and the Long-Term Impact of Cancer and Its Treatment
A1  - Roschewski, Mark
A1  - Longo, Dan L.
A2  - Loscalzo, Joseph
A2  - Fauci, Anthony
A2  - Kasper, Dennis
A2  - Hauser, Stephen
A2  - Longo, Dan
A2  - Jameson, J. Larry
Y1  - 2022
N1  - 
T2  - Harrison's Principles of Internal Medicine, 21e
AB  - The  impact  of  cancer  extends  well  past  initial  diagnosis.  Patients  are  significantly  affected  by  cancer  and  treatment-related  toxicities  often  extending  beyond  the  initial  treatment  period.  Adult  survivors  of  childhood,  adolescent,  and  young  adult  cancer  face  special  health  consequences  of  cancer  treatment  related  to  premature  physiologic  aging  and  frailty.  More  than  40%  of  these  patients  will  experience  a  severe,  disabling,  or  life-threatening  condition  or  die  of  a  chronic  condition.  Long-term  effects  include  toxicities  that  emerge  during  therapy  and  continue  beyond  treatment,  while  late  effects  include  toxicities  that  may  not  emerge  for  months  or  years  after  treatment.  Significant  improvements  in  cancer  treatments  have  enabled  more  people  to  survive  once-deadly  diseases,  leading  to  more  cancer  survivors  subjected  to  the  potential  long-term  impact  of  cancer  treatment  (Table  95-1  lists  potential  long-term  and  late  effects  of  cancer  therapy  by  organ  system).  The  direct  causality  of  emerging  treatments  may  not  be  immediately  evident,  and  pharmacovigilance  remains  critical  after  treatments  first  become  approved.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1190481752
ER  -