TY  - CHAP
M1  - Book, Section
TI  - Cancer of the Skin
A1  - Curti, Brendan D.
A1  - Vetto, John T.
A1  - Leachman, Sancy A.
A2  - Loscalzo, Joseph
A2  - Fauci, Anthony
A2  - Kasper, Dennis
A2  - Hauser, Stephen
A2  - Longo, Dan
A2  - Jameson, J. Larry
Y1  - 2022
N1  - 
T2  - Harrison's Principles of Internal Medicine, 21e
AB  - Pigmented  lesions  are  among  the  most  common  findings  on  skin  examination.  The  challenge  for  the  physician  is  to  distinguish  benign  lesions  from  cutaneous  melanomas  and  nonmelanoma  skin  cancers  (NMSCs).  Both  melanoma  and  NMSC  are  increasing  in  frequency,  and  melanoma  accounts  for  over  half  of  the  deaths  resulting  from  skin  cancer.  Melanoma  is  an  aggressive  malignancy  of  melanocytes,  pigment-producing  cells  that  originate  from  the  neural  crest  and  migrate  to  the  skin,  meninges,  mucous  membranes,  upper  esophagus,  and  eyes.  Melanocytes  in  each  of  these  locations  have  the  potential  for  malignant  transformation,  but  the  vast  majority  of  melanomas  arise  in  the  skin,  often  permitting  detection  at  a  time  when  complete  surgical  excision  leads  to  cure.  Cutaneous  melanoma  can  occur  in  people  of  all  ages  and  all  colors.  Examples  of  malignant  melanoma  of  the  skin,  mucosa,  eye,  and  nail  are  shown  in  Fig.  76-1.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/25
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1196992686
ER  -