TY  - CHAP
M1  - Book, Section
TI  - Marijuana & Synthetic Cannabinoids
A1  - Smollin, Craig
A2  - Papadakis, Maxine A.
A2  - McPhee, Stephen J.
A2  - Rabow, Michael W.
A2  - McQuaid, Kenneth R.
Y1  - 2022
N1  - 
T2  - Current Medical Diagnosis & Treatment 2022
AB  - Marijuana  refers  to  the  crushed  dried  leaves  and  flowers  of  the  Cannabis  plant.  These  dried  leaves  and  flowers  contain  the  psychoactive  cannabinoid  delta-9-tetrahydrocannabinal  (THC),  which  binds  to  endogenous  cannabinoid  receptors.  Marijuana  is  usually  smoked  in  cigarettes  or  pipes  but  may  also  be  vaporized  or  added  to  a  variety  of  foods,  beverages,  and  candies.  Resin  from  the  plant  may  be  dried  and  pressed  into  blocks  called  hashish,  and  solvents  may  be  used  to  extract  THC  into  highly  concentrated  oils  (butane  hash  oil).  THC  has  been  used  medically  as  an  appetite  stimulant,  as  an  antiemetic,  and  in  the  treatment  of  a  variety  of  medical  conditions.  It  has  now  been  legalized  for  both  medical  and  recreational  use  in  an  increasing  number  of  US  states  (https://disa.com/map-of-marijuana-legality-by-state).  Toxicity  is  dose  dependent  but  varies  significantly  by  individual,  prior  experience,  and  degree  of  tolerance.  Synthetic  cannabinoids  (“Spice,”  “K2,”  “Black  Mamba”)  are  laboratory  designed  analogs  of  THC.  They  have  become  increasingly  popular  and  are  associated  with  a  variety  of  adverse  side  effects,  including  seizures,  kidney  dysfunction,  and  serious  neuropsychiatric  symptoms.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/24
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1184179737
ER  -