TY - CHAP M1 - Book, Section TI - Increased Platelet Destruction A1 - Leavitt, Andrew D. A1 - Price, Erika Leemann A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. Y1 - 2022 N1 - T2 - Current Medical Diagnosis & Treatment 2022 AB - KEY CLINICAL UPDATES IN INCREASED PLATELET DESTRUCTIONThe role of caplacizumab in the treatment of thrombotic thrombocytopenic purpura remains controversial given its high cost and limited benefit, despite its inclusion in 2020 guidelines.Careful monitoring of the ADAMTS-13 activity and inhibitor status and use of rituximab can prevent dangerous relapses. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184168526 ER -