TY  - CHAP
M1  - Book, Section
TI  - Pure Red Cell Aplasia
A1  - Damon, Lloyd E.
A1  - Andreadis, Charalambos Babis
A2  - Papadakis, Maxine A.
A2  - McPhee, Stephen J.
A2  - Rabow, Michael W.
A2  - McQuaid, Kenneth R.
Y1  - 2022
N1  - 
T2  - Current Medical Diagnosis & Treatment 2022
AB  - Acquired  pure  red  cell  aplasia  is  rare.  It  is  an  autoimmune  disease  mediated  by  T  lymphocytes  and/or  by  an  IgG  antibody  against  erythroid  precursors  in  the  bone  marrow.  In  adults,  the  disease  is  usually  idiopathic.  However,  cases  have  been  seen  in  association  with  systemic  lupus  erythematosus,  chronic  lymphocytic  leukemia  (CLL),  lymphomas,  or  thymoma.  Some  medications  (phenytoin,  chloramphenicol)  may  cause  red  cell  aplasia.  Rarely,  anti-erythropoietin  antibodies  cause  pure  red  cell  aplasia  in  patients  who  are  treated  with  recombinant  erythropoietin.  Transient  episodes  of  red  cell  aplasia  are  probably  common  in  response  to  viral  infections,  especially  parvovirus  infections.  However,  these  acute  episodes  will  go  unrecognized  unless  the  patient  has  a  chronic  hemolytic  disorder  or  a  chronic  immunocompromised  state,  in  which  case  the  hematocrit  may  fall  precipitously.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2023/09/30
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1184165754
ER  -